Nanosafety Cluster Training Day

16 + 23 Nov 2020

This day acted as guidance for the entire NanoSafety community, including young researchers, to highlight how individual research projects fit as a puzzle piece into the wider picture. It shall be an orientation-giving and educational event depicting the overall strategy behind NanoSafe(ty).

Full playlist

Education day

Block 1 – Emerging approaches in nanorisk assessment

Session 1: New developments in human hazard assessment – focus on AOP, QSAR, IATA

  • Session intro on “The Why and What and How of AOPs and various emerging approaches – QSAR, NAMs, IATA” by Session Chair Peter Hoet, KathUni Leuven
  • “Beyond chemocentric models: from toxicogenomics to integrated approaches for IATA development” by Dario Greco, Uni Tampere
  • AOPs and data integration within Nanosafety” by Penny Nymark, Karolisnka Institutet
  • Showcasing the AOP-Wiki Resource Description Framework – why nano-AOPs do not exist” by Marvin Martens, Uni Maastricht

Session 1 - New developments in human hazard assessment: focus on AOP, QSAR, IATA

Session 2: Exposure & life cycle assessment – determination & modeling

  • Introduction of Session Chair Wouter Fransman, TNO
  • “Extrapolation (i.e. re-use) of exposure measurement data for similar exposure scenarios and/or similar materials – from regular chemicals to NMs” by Remy Franken, TNO
  • “Sharing of release and exposure measurement data” by Camilla Delpivo, Leitat
  • “Efficiency testing and implementation of risk management measures to mitigate exposure to NMs” by Henk Goede, TNO
  • “Life cycle thinking in nanoform release assessment” by Nathan Bossa, Leitat

Session 2 - Exposure & life cycle assessment - determination & modelling

Block 2 – Data workshop & e-tools for nano & beyond

Session 3: Data FAIRness, metadata completeness, scientific quality assurance

  • Session intro “Experiences from NanoFASE going FAIR” by Session Chair Claus Svendsen, UKCEH
  • “When is a metadata set complete?” showcasing (a) specific example(s) with discussion moderated by Thomas Exner, Edelweiss Connect
  • “How to implement (scientific) FAIR principles in my work?” showcasing support in data FAIRness for projects by Ammar Ammar, Uni Maastrich

Session 3 - Data FAIRness, metadata completeness, scientific quality assurance

Session 4: Spectrum of e-tools along data life cycle

  • Session intro “Data life cycle – generation processing, evaluation, prediction, curation” by Session Chair Iseult Lynch, UoB
  • “Showcasing the NanoCommons exposure/risk assessment tool: http://enaloscloud.novamechanics.com/nanocommons/exposure/” by Periklis Tsiros, Harry Sarimveis, NTUA
  • “Showcasing read-across of NM properties (i.e. zeta potential) to cytotoxicity using NanoSolveIT’s and NanoCommons nanoinformatics models” by Tassos Papadiamantis, UoB, NovaMechanics, Georgia Melagraki, Antreas Afantitis NovaMechanics
  • “Showcasing NanoSolveIT’s human exposure assessment” by Nikolaos Cheimarios, Andreas Tsoumanis, Georgia Melagraki, Antreas Afantitis, NovaMechanics
  • “Idea, methodology, current state of the NanoInformaTIX platform” by Gianpetro Basei, Greendecision
  • “Call for action on the Gracious Ontology-Wiki” by Thomas Exner, Edelweiss Connect

Session 4 - Spectrum of e-tools along data life cycle

Block 3 – NanoRisk Governance & Safe-by-Design concepts – fit for translation to sustainable development?

Session 5: Features of nanoRGFs in development & current NRGC concepts

  • “What do we need a NRG Council for, who are its stakeholders and what are their needs?” by Marie-Valentin Florin, NanoRigo
  • “What can we expect from a future NRG Council and what is the current view on its design” by Rob Aitken, Gov4Nano
  • “Screening ethical issues for governance of nanorisk” by Ineke Malsh, RiskGone
  • “Insight into the nanorisk governance process guided by the NanoRigo NRG framework” by Arto Säämänen, and “Requirements on NRG frameworks by insurances and other societal stakeholders” by Martin Mullins, NanoRigo

Session 5 - Features of nanoRGFs in development & current NRGC concepts

Session 6: Elements of SbD for sustainable development & innovation

  • Session intro “SbD – from philosophy to application” by Session Chair Andrew Nelson (SABYDOMA)
  • “Elevator pitches by other 3 NMBP-15 projects” by Soco Vazquez (SABYNA), Carlos Fito (SbD4Nano), Anna Costa (ASINA)
  • “Presenting two case studies (CS) to apply different SbD concepts: (a) CS1 on SbD for Covid-19: antiviral coating, strategies for pharma” by Anna Costa; arising questions for SbD application in CS1
  • “CS2 on SbD in plastics/3D printing/additive manufacturing” by Soco Vazquez; arising questions for SbD applications in CS2
  • General discussion of views/feelings moderated by Susanne Resch, BNN, for CS1 and Soco Vazquez, Leitat, for CS2
  • Session summary & outlook to green innovation jointly by Andrew Nelson and Martin Himly

Session 6 - Elements of SbD for sustainable development & innovation

Training day

Hands-on Training - Nanosafety Tools and Models morning #1 In silico tools for Nanosafety Research, Lang Tran (PATROLS)

Hands-on Training - Nanosafety Tools and Models morning #2 Interactive training on “NanoXtract Image Analysis Tool – NanoCommons Knowledge Base”, Antreas Afantitis, Georgia Melagraki, Dieter Maier, Andreas Tsoumanis, Anastasios Papadiamantis, Iseult Lynch (NanoCommons)

Hands-on Training - Nanosafety Tools and Models afternoon #1 NanoSolveIT tools for assessment of human and environmental exposure to nanomaterials Antreas Afantitis, Georgia Melagraki, Nikolaos Cheimarios, Andreas Tsoumanis, Samuel Harisson, Pantelis Karatzas, Philip Doganis, Harry Sarimveis, Iseult Lynch (NanoSolveIT)

Hands-on Training - Nanosafety Tools and Models afternoon #2 Advanced in vitro models of the human lung, GI tract & liver for hazard characterisation, Kirsty Meldrum, Barbara Drasler, Rui-Wen He, Angela Kämpfer, Samantha Victoria Llewellyn, Marije Niemeijer (PATROLS)

Stakeholder Engagement: Regulation and Risk Governance Introduction to Nanotechnology Regulations & Risk Governance (NSC Working Group G), Steffi Friedrichs (AcumenIST), Keld Alstrup Jensen (caLIBRAte), Monique Groenewold (Gov4Nano), Thomas Kuhlbusch (NanoHarmony) Maria Dusinska (RiskGONE), Janeck Scott-Fordsmand (NanoRIGO) (NANOMET), Miguel Banares (NanoInformaTIX), Antreas Afantitis (NanoSolveIT), Iseult Lynch (NanoCommons)

Stakeholder engagement: Science Diplomacy A New Way to Think About Your Role in a Community of Research, Claire Mays (SabyNA, InsSciDE), Guillermo Ort-Gils, Institute for Bioengineering of Catalonia (IBEC)